Tavern Brawler Throwing Stack

Gameplay loop
Thiefzerker is incredibly simple to pilot:

Enrage(Frenzy) right away

Use Action Surge if you have it

Spend all actions on Throw

Spend all bonus actions on Enraged Throw

One respec at level 8, and 2 more in the late game are ideal, and is what I recommend.
When you do your late game respec, you should take 4 fighter / 3 rogue. Slight HP gain at no cost.

Once you hit level 8, respec.
Follow the same steps as above, but this time, stop at level 5.
Then open Rogue, and level it to 3.
Take the Thief subclass. After your respec, you should be at 5 Barb/3 Rogue.
At level 9, put another level in Rogue to get your second Feat, and take Dual Wielder.
At level 10, open Fighter. For fighting style, take Defense.
You’ll put your last two levels in Fighter, and pick a subclass at level 3.

https://www.reddit.com/r/BG3Builds/comments/18eguld/honor_mode_tb_throw_complete_build_guide/